CompositionPiperazine (771.42 mg)
SALT INFORMATIONPiperazine (771.42 mg) TYPICAL USAGE Threadworm, roundworm and pinworm infections. SIDE EFFECTS Nausea, vomiting, colic, abdominal pain, diarrhoea, urticaria, skin rashes, headache, bronchospasm, dizziness, nystagmus, ataxia, myoclonic contractions, choreiform movements, muscular incoordination (worm wobble), confusion, EEG abnormalities. DRUG INTERACTION Piperazine is known to interact with other drugs like Bephenium Hydroxynaphthoate, Chlorpromazine (HCl), Methotrimeprazine (Maleate), Pyrantel Pamoate, Sulpiride. MECHANISM OF ACTION It is effective against the intestinal nematodes roundworm (Ascaris lumbricoides), pinworm and threadworm (Enterobius vermicularis). Piperazine produces a neuromuscular block leads to muscle paralysis of the worms which are consequently dislodged and expelled in the faeces.